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Published in Modern Aesthetics—The Heritage of Platelet-Derived Growth Factor

Lynch SE

Published on February 17, 2026

The Heritage of Platelet-Derived Growth Factor (Lynch SE, 2025) Modern Aesthetics; Nov 2025

In this article published in Modern Aesthetics, Dr. Lynch discusses the legacy of PDGF, ethical frameworks for emerging science, the emphasis on “data over dogma”, and the importance of protecting discovery and innovation.

From its discovery nearly half a century ago to its current place in patient care and scientific conversation in aesthetic medicine, poorly healing skin wounds, orthopedics, and dental surgical reconstruction, platelet-derived growth factor (PDGF) stands as both a milestone of molecular biology and a reminder of the professional responsibilities that accompany innovation.

DISCLAIMER: The accompanying article discusses approved and unapproved uses of recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB or PDGF). Unapproved uses of PDGF have not been approved by the FDA, and the safety and effectiveness of PDGF for such unapproved uses have not been established. The article is provided for informational and scientific discussion purposes only and does not constitute promotion of any unapproved product or use.

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The Heritage of Platelet-Derived Growth Factor, Samuel Lynch, DMSc, DMD, Published in Modern Aesthetics
Lynch Regenerative Medicine
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